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The role of autophagy in the treatment of BRAF mutant colorectal carcinomas differs based on microsatellite instability status

Autophagy has been identified as a catabolic mechanism in cells but its’ role in cancer remains controversial. Autophagy has been characterized either as tumor suppressor or inducer mechanism in many tumor types. Monoclonal antibodies against EGFR (cetuximab and panitumumab) represent a major step i...

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Detalles Bibliográficos
Autores principales: Koustas, Evangelos, Papavassiliou, Athanasios G., Karamouzis, Michalis V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241137/
https://www.ncbi.nlm.nih.gov/pubmed/30427914
http://dx.doi.org/10.1371/journal.pone.0207227