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The role of autophagy in the treatment of BRAF mutant colorectal carcinomas differs based on microsatellite instability status
Autophagy has been identified as a catabolic mechanism in cells but its’ role in cancer remains controversial. Autophagy has been characterized either as tumor suppressor or inducer mechanism in many tumor types. Monoclonal antibodies against EGFR (cetuximab and panitumumab) represent a major step i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241137/ https://www.ncbi.nlm.nih.gov/pubmed/30427914 http://dx.doi.org/10.1371/journal.pone.0207227 |