CX-3543 Promotes Cell Apoptosis through Downregulation of CCAT1 in Colon Cancer Cells

AIM: Colon cancer-associated transcript-1 (CCAT1), located in the vicinity of transcription factor c-Myc, was first identified in colon cancer. A small-molecule compound CX3543 (Quarfloxin) selectively targeting Myc G-quadruplexes has entered phase II clinical trials for neuroendocrine carcinomas. T...

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Detalles Bibliográficos
Autores principales: Yao, Yu-xia, Xu, Bao-hong, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241339/
https://www.ncbi.nlm.nih.gov/pubmed/30519593
http://dx.doi.org/10.1155/2018/9701957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241339/
https://www.ncbi.nlm.nih.gov/pubmed/30519593
http://dx.doi.org/10.1155/2018/9701957

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