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Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

OBJECTIVE: Accumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity, leading to non-alcoholic fatty liver disease (NAFLD). This study aimed to investigate the underlying mechanisms by which FFA contributes to the pathogenesis of NAFLD via the regulation of 3-mercaptopyruvate sulfu...

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Detalles Bibliográficos
Autores principales: Li, Meng, Xu, Chengfu, Shi, Junping, Ding, Jiexia, Wan, Xingyong, Chen, Dahua, Gao, Jianguo, Li, Chunxiao, Zhang, Jie, Lin, Yiming, Tu, Zhenhua, Kong, Xiaoni, Li, Youming, Yu, Chaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241611/
https://www.ncbi.nlm.nih.gov/pubmed/28877979
http://dx.doi.org/10.1136/gutjnl-2017-313778