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Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia

OBJECTIVE: DNA-based testing of pancreatic cyst fluid (PCF) is a useful adjunct to the evaluation of pancreatic cysts (PCs). Mutations in KRAS/GNAS are highly specific for intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs), while TP53/PIK3CA/PTEN alterations are as...

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Detalles Bibliográficos
Autores principales: Singhi, Aatur D, McGrath, Kevin, Brand, Randall E, Khalid, Asif, Zeh, Herbert J, Chennat, Jennifer S, Fasanella, Kenneth E, Papachristou, Georgios I, Slivka, Adam, Bartlett, David L, Dasyam, Anil K, Hogg, Melissa, Lee, Kenneth K, Marsh, James Wallis, Monaco, Sara E, Ohori, N Paul, Pingpank, James F, Tsung, Allan, Zureikat, Amer H, Wald, Abigail I, Nikiforova, Marina N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241612/
https://www.ncbi.nlm.nih.gov/pubmed/28970292
http://dx.doi.org/10.1136/gutjnl-2016-313586