Intrarenal activation of adaptive immune effectors is associated with tubular damage and impaired renal function in lupus nephritis

OBJECTIVES: Chronic renal impairment remains a feared complication of lupus nephritis (LN). The present work aimed at identifying mechanisms and markers of disease severity in renal tissue samples from patients with LN. METHODS: We performed high-throughput transcriptomic studies (Illumina HumanHT-1...

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Detalles Bibliográficos
Autores principales: Pamfil, Cristina, Makowska, Zuzanna, De Groof, Aurélie, Tilman, Gaëlle, Babaei, Sepideh, Galant, Christine, Montigny, Pauline, Demoulin, Nathalie, Jadoul, Michel, Aydin, Selda, Lesche, Ralf, McDonald, Fiona, Houssiau, Frédéric A, Lauwerys, Bernard R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241616/
https://www.ncbi.nlm.nih.gov/pubmed/30065042
http://dx.doi.org/10.1136/annrheumdis-2018-213485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241616/
https://www.ncbi.nlm.nih.gov/pubmed/30065042
http://dx.doi.org/10.1136/annrheumdis-2018-213485

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