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Intrarenal activation of adaptive immune effectors is associated with tubular damage and impaired renal function in lupus nephritis
OBJECTIVES: Chronic renal impairment remains a feared complication of lupus nephritis (LN). The present work aimed at identifying mechanisms and markers of disease severity in renal tissue samples from patients with LN. METHODS: We performed high-throughput transcriptomic studies (Illumina HumanHT-1...
Autores principales: | Pamfil, Cristina, Makowska, Zuzanna, De Groof, Aurélie, Tilman, Gaëlle, Babaei, Sepideh, Galant, Christine, Montigny, Pauline, Demoulin, Nathalie, Jadoul, Michel, Aydin, Selda, Lesche, Ralf, McDonald, Fiona, Houssiau, Frédéric A, Lauwerys, Bernard R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241616/ https://www.ncbi.nlm.nih.gov/pubmed/30065042 http://dx.doi.org/10.1136/annrheumdis-2018-213485 |
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