Arsenic sulfide amplifies JQ1 toxicity via mitochondrial pathway in gastric and colon cancer cells

PURPOSE: Gastric and colon cancers have been the leading causes of cancer mortality in the world with limited therapy. Small molecules binding to bromodomains of bromodomain-containing protein 4 (BRD4) exert strong antitumor activities against hematological malignancies, while generally have limited...

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Detalles Bibliográficos
Autores principales: Tan, Zhen, Zhang, Xiuli, Kang, Ting, Zhang, Lian, Chen, Siyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241694/
https://www.ncbi.nlm.nih.gov/pubmed/30532520
http://dx.doi.org/10.2147/DDDT.S180976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241694/
https://www.ncbi.nlm.nih.gov/pubmed/30532520
http://dx.doi.org/10.2147/DDDT.S180976

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