Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs

BACKGROUND: Gefitinib (Gef), an important epidermal growth factor receptor (EGFR), is used to treat lung cancer, but low water solubility and poor bioavailability severely limit its application in cancer therapy. METHODS: In this study, nanographene oxide (NGO) was decorated with hyaluronic acid (HA...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Zhang, Doudou, Lian, Shu, Zheng, Junxia, Li, Bifei, Li, Tao, Jia, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241762/
https://www.ncbi.nlm.nih.gov/pubmed/30532533
http://dx.doi.org/10.2147/IJN.S173889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241762/
https://www.ncbi.nlm.nih.gov/pubmed/30532533
http://dx.doi.org/10.2147/IJN.S173889

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