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Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs
BACKGROUND: Gefitinib (Gef), an important epidermal growth factor receptor (EGFR), is used to treat lung cancer, but low water solubility and poor bioavailability severely limit its application in cancer therapy. METHODS: In this study, nanographene oxide (NGO) was decorated with hyaluronic acid (HA...
Autores principales: | Liu, Jian, Zhang, Doudou, Lian, Shu, Zheng, Junxia, Li, Bifei, Li, Tao, Jia, Lee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241762/ https://www.ncbi.nlm.nih.gov/pubmed/30532533 http://dx.doi.org/10.2147/IJN.S173889 |
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