Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer

BACKGROUND: Multidrug resistance (MDR) is the major reason for the failure of chemotherapy in colon cancer. Bufalin (BU) is one of the most effective antitumor active constituents in Chansu. Our previous study found that BU can effectively reverse P-glycoprotein (P-gp)-mediated MDR in colon cancer....

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Detalles Bibliográficos
Autores principales: Yuan, Zeting, Yuan, Yuxia, Han, Lin, Qiu, Yanyan, Huang, Xiaqin, Gao, Feng, Fan, Guohua, Zhang, Yixi, Tang, Xueyao, He, Xue, Xu, Ke, Yin, Peihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241863/
https://www.ncbi.nlm.nih.gov/pubmed/30532537
http://dx.doi.org/10.2147/IJN.S170692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241863/
https://www.ncbi.nlm.nih.gov/pubmed/30532537
http://dx.doi.org/10.2147/IJN.S170692

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