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Klf5 suppresses ERK signaling in mouse pluripotent stem cells

Mouse embryonic stem cells (ESCs) are pluripotent stem cells, which have the ability to differentiate into all three germ layers: mesoderm, endoderm, and ectoderm. Proper levels of phosphorylated extracellular signal-regulated kinase (pERK) are critical for maintaining pluripotency, as elevated pERK...

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Detalles Bibliográficos
Autores principales: Azami, Takuya, Matsumoto, Ken, Jeon, Hyojung, Waku, Tsuyoshi, Muratani, Masafumi, Niwa, Hitoshi, Takahashi, Satoru, Ema, Masatsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242311/
https://www.ncbi.nlm.nih.gov/pubmed/30452437
http://dx.doi.org/10.1371/journal.pone.0207321