Features of interactions responsible for antifungal activity against resistant type cytochrome bc1: A data-driven analysis based on the binding free energy at the atomic level

Quinone outside inhibitors (QoIs), which inhibit the mitochondrial respiratory system by binding to the Qo site of Complex III in fungi, are widely used as pesticides with broad spectrum antifungal activity. However, excessive use of QoIs leads to pesticide resistance through mutation of amino acid...

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Detalles Bibliográficos
Autores principales: Arakawa, Akihiko, Kasai, Yukako, Yamazaki, Kazuto, Iwahashi, Fukumatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242680/
https://www.ncbi.nlm.nih.gov/pubmed/30452473
http://dx.doi.org/10.1371/journal.pone.0207673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242680/
https://www.ncbi.nlm.nih.gov/pubmed/30452473
http://dx.doi.org/10.1371/journal.pone.0207673

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