Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery

In response to genotoxic stress, cells activate a signaling cascade known as the DNA damage checkpoint (DDC) that leads to a temporary cell cycle arrest and activation of DNA repair mechanisms. Because persistent DDC activation compromises cell viability, this process must be tightly regulated. Howe...

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Detalles Bibliográficos
Autores principales: Millan-Zambrano, Gonzalo, Santos-Rosa, Helena, Puddu, Fabio, Robson, Samuel C., Jackson, Stephen P., Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242705/
https://www.ncbi.nlm.nih.gov/pubmed/30454561
http://dx.doi.org/10.1016/j.molcel.2018.09.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242705/
https://www.ncbi.nlm.nih.gov/pubmed/30454561
http://dx.doi.org/10.1016/j.molcel.2018.09.023

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