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Phosphorylation of Histone H4T80 Triggers DNA Damage Checkpoint Recovery
In response to genotoxic stress, cells activate a signaling cascade known as the DNA damage checkpoint (DDC) that leads to a temporary cell cycle arrest and activation of DNA repair mechanisms. Because persistent DDC activation compromises cell viability, this process must be tightly regulated. Howe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242705/ https://www.ncbi.nlm.nih.gov/pubmed/30454561 http://dx.doi.org/10.1016/j.molcel.2018.09.023 |