The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination

Class switch recombination (CSR) is a DNA recombination reaction that diversifies the effector component of antibody responses. CSR is initiated by activation-induced cytidine deaminase (AID), which targets transcriptionally active immunoglobulin heavy chain (Igh) switch donor and acceptor DNA. The...

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Detalles Bibliográficos
Autores principales: Delgado-Benito, Verónica, Rosen, Daniel B., Wang, Qiao, Gazumyan, Anna, Pai, Joy A., Oliveira, Thiago Y., Sundaravinayagam, Devakumar, Zhang, Wenzhu, Andreani, Matteo, Keller, Lisa, Kieffer-Kwon, Kyong-Rim, Pękowska, Aleksandra, Jung, Seolkyoung, Driesner, Madlen, Subbotin, Roman I., Casellas, Rafael, Chait, Brian T., Nussenzweig, Michel C., Di Virgilio, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242708/
https://www.ncbi.nlm.nih.gov/pubmed/30293785
http://dx.doi.org/10.1016/j.molcel.2018.08.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242708/
https://www.ncbi.nlm.nih.gov/pubmed/30293785
http://dx.doi.org/10.1016/j.molcel.2018.08.042

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