Proteolysis of ToxR is controlled by cysteine‐thiol redox state and bile salts in Vibrio cholerae

In Vibrio cholerae, virulence gene expression is regulated by a transmembrane‐localized transcription factor complex designated as ToxRS. ToxR harbours two cysteines in the periplasmic domain that can form inter‐ and intramolecular disulfide bonds. In this study, we investigated the σ(E)‐dependent i...

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Detalles Bibliográficos
Autores principales: Lembke, Mareike, Pennetzdorfer, Nina, Tutz, Sarah, Koller, Michael, Vorkapic, Dina, Zhu, Jun, Schild, Stefan, Reidl, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242745/
https://www.ncbi.nlm.nih.gov/pubmed/30218472
http://dx.doi.org/10.1111/mmi.14125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242745/
https://www.ncbi.nlm.nih.gov/pubmed/30218472
http://dx.doi.org/10.1111/mmi.14125

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