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Polymer Simulations of Heteromorphic Chromatin Predict the 3D Folding of Complex Genomic Loci
Chromatin folded into 3D macromolecular structures is often analyzed by chromosome conformation capture (3C) and fluorescence in situ hybridization (FISH) techniques, but these frequently provide contradictory results. Chromatin can be modeled as a simple polymer composed of a connected chain of uni...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242782/ https://www.ncbi.nlm.nih.gov/pubmed/30344096 http://dx.doi.org/10.1016/j.molcel.2018.09.016 |