H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression

Epigenetic regulators are attractive anticancer targets, but the promise of therapeutic strategies inhibiting some of these factors has not been proven in vivo or taken into account tumor cell heterogeneity. Here we show that the histone methyltransferase G9a, reported to be a therapeutic target in...

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Detalles Bibliográficos
Autores principales: Rowbotham, S. P., Li, F., Dost, A. F. M., Louie, S. M., Marsh, B. P., Pessina, P., Anbarasu, C. R., Brainson, C. F., Tuminello, S. J., Lieberman, A., Ryeom, S., Schlaeger, T. M., Aronow, B. J., Watanabe, H., Wong, K. K., Kim, C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242814/
https://www.ncbi.nlm.nih.gov/pubmed/30455465
http://dx.doi.org/10.1038/s41467-018-07077-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242814/
https://www.ncbi.nlm.nih.gov/pubmed/30455465
http://dx.doi.org/10.1038/s41467-018-07077-1

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