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Engulfing cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1

Two important biological events happen coincidently soon after nerve injury in the peripheral nervous system in C. elegans: removal of axon debris and initiation of axon regeneration. But, it is not known how these two events are co-regulated. Mutants of ced-1, a homolog of Draper and MEGF10, displa...

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Detalles Bibliográficos
Autores principales: Chiu, Hui, Zou, Yan, Suzuki, Nobuko, Hsieh, Yi-Wen, Chuang, Chiou-Fen, Wu, Yi-Chun, Chang, Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242819/
https://www.ncbi.nlm.nih.gov/pubmed/30451835
http://dx.doi.org/10.1038/s41467-018-07291-x