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Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes

Frataxin is a highly conserved protein encoded by the frataxin (FXN) gene. The full-length 210-amino acid form of protein frataxin (1–210; isoform A) expressed in the cytosol of cells rapidly translocates to the mitochondria, where it is converted to the mature form (81–210) by mitochondrial process...

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Detalles Bibliográficos
Autores principales: Guo, Lili, Wang, Qingqing, Weng, Liwei, Hauser, Lauren A., Strawser, Cassandra J., Mesaros, Clementina, Lynch, David R., Blair, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242848/
https://www.ncbi.nlm.nih.gov/pubmed/30451920
http://dx.doi.org/10.1038/s41598-018-35346-y