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Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells

Circulating monocytes can compete for virtually any tissue macrophage niche and become long-lived replacements that are phenotypically indistinguishable from their embryonic counterparts. As the factors regulating this process are incompletely understood, we studied niche competition in the brain by...

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Detalles Bibliográficos
Autores principales: Lund, Harald, Pieber, Melanie, Parsa, Roham, Han, Jinming, Grommisch, David, Ewing, Ewoud, Kular, Lara, Needhamsen, Maria, Espinosa, Alexander, Nilsson, Emma, Överby, Anna K., Butovsky, Oleg, Jagodic, Maja, Zhang, Xing-Mei, Harris, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242869/
https://www.ncbi.nlm.nih.gov/pubmed/30451869
http://dx.doi.org/10.1038/s41467-018-07295-7