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Access to high-impact mutations constrains the evolution of antibiotic resistance in soft agar
Despite widespread resistance to many important antibiotics, the factors that govern the emergence and prevalence of antibiotic-resistant bacteria are still unclear. When exposed to antibiotic gradients in soft agar plates measuring as little as 1.25 × 11 cm we found that Escherichia coli rapidly be...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242871/ https://www.ncbi.nlm.nih.gov/pubmed/30451932 http://dx.doi.org/10.1038/s41598-018-34911-9 |