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Enhanced Cytotoxic Activity of Mitochondrial Mechanical Effectors in Human Lung Carcinoma H520 Cells: Pharmaceutical Implications for Cancer Therapy

Cancer cell mitochondria represent an attractive target for oncological treatment as they have unique hallmarks that differ from their healthy counterparts, as the presence of a stronger membrane potential that can be exploited to specifically accumulate cytotoxic cationic molecules. Here, we explor...

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Detalles Bibliográficos
Autores principales: González Rubio, Sergio, Montero Pastor, Nuria, García, Carolina, Almendro-Vedia, Víctor G., Ferrer, Irene, Natale, Paolo, Paz-Ares, Luis, Lillo, M. Pilar, López-Montero, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242888/
https://www.ncbi.nlm.nih.gov/pubmed/30483474
http://dx.doi.org/10.3389/fonc.2018.00514