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Synthetic RNA-based logic computation in mammalian cells

Synthetic biological circuits are designed to regulate gene expressions to control cell function. To date, these circuits often use DNA-delivery methods, which may lead to random genomic integration. To lower this risk, an all RNA system, in which the circuit and delivery method are constituted of R...

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Detalles Bibliográficos
Autores principales: Matsuura, Satoshi, Ono, Hiroki, Kawasaki, Shunsuke, Kuang, Yi, Fujita, Yoshihiko, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242901/
https://www.ncbi.nlm.nih.gov/pubmed/30451868
http://dx.doi.org/10.1038/s41467-018-07181-2