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Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling

Canonical Wnt signaling is crucial for vascularization of the central nervous system and blood-brain barrier (BBB) formation. BBB formation and modulation are not only important for development, but also relevant for vascular and neurodegenerative diseases. However, there is little understanding of...

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Detalles Bibliográficos
Autores principales: Hübner, Kathleen, Cabochette, Pauline, Diéguez-Hurtado, Rodrigo, Wiesner, Cora, Wakayama, Yuki, Grassme, Kathrin S., Hubert, Marvin, Guenther, Stefan, Belting, Heinz-Georg, Affolter, Markus, Adams, Ralf H., Vanhollebeke, Benoit, Herzog, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242933/
https://www.ncbi.nlm.nih.gov/pubmed/30451830
http://dx.doi.org/10.1038/s41467-018-07302-x