Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis

Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this inflammatory condition via a cytotoxic response on intestinal epithelial cells (IECs), but the underlying mechanisms are incompletely understood. Addi...

Descripción completa

Detalles Bibliográficos
Autores principales: Saavedra, Pedro H. V., Huang, Linyan, Ghazavi, Farzaneh, Kourula, Stephanie, Vanden Berghe, Tom, Takahashi, Nozomi, Vandenabeele, Peter, Lamkanfi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242954/
https://www.ncbi.nlm.nih.gov/pubmed/30451870
http://dx.doi.org/10.1038/s41467-018-07386-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242954/
https://www.ncbi.nlm.nih.gov/pubmed/30451870
http://dx.doi.org/10.1038/s41467-018-07386-5

Ejemplares similares