Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice

The aim was to clarify the role of vimentin, an intermediate filament protein abundantly expressed in activated macrophages and foam cells, in macrophages during atherogenesis. Global gene expression, lipid uptake, ROS, and inflammation were analyzed in bone-marrow derived macrophages from vimentin-...

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Detalles Bibliográficos
Autores principales: Håversen, Liliana, Sundelin, Jeanna Perman, Mardinoglu, Adil, Rutberg, Mikael, Ståhlman, Marcus, Wilhelmsson, Ulrika, Hultén, Lillemor Mattsson, Pekny, Milos, Fogelstrand, Per, Bentzon, Jacob Fog, Levin, Malin, Borén, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242955/
https://www.ncbi.nlm.nih.gov/pubmed/30451917
http://dx.doi.org/10.1038/s41598-018-34659-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242955/
https://www.ncbi.nlm.nih.gov/pubmed/30451917
http://dx.doi.org/10.1038/s41598-018-34659-2

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