Decreased BDNF Release in Cortical Neurons of a Knock-in Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease caused by an increase in CAG repeats in the Huntingtin gene (HTT). The striatum is one of the most vulnerable brain regions in HD, and altered delivery of BDNF to the striatum is believed to underlie this high vulnerabilit...

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Detalles Bibliográficos
Autores principales: Yu, Chenglong, Li, Chun Hei, Chen, Sidong, Yoo, Hanna, Qin, Xianan, Park, Hyokeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242964/
https://www.ncbi.nlm.nih.gov/pubmed/30451892
http://dx.doi.org/10.1038/s41598-018-34883-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242964/
https://www.ncbi.nlm.nih.gov/pubmed/30451892
http://dx.doi.org/10.1038/s41598-018-34883-w

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