Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain

Kainate-type glutamate receptors play critical roles in excitatory synaptic transmission and synaptic plasticity in the brain. GluK1 and GluK2 possess fundamentally different capabilities in surface trafficking as well as synaptic targeting in hippocampal CA1 neurons. Here we find that the excitator...

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Detalles Bibliográficos
Autores principales: Duan, Gui-Fang, Ye, Yaxin, Xu, Sha, Tao, Wucheng, Zhao, Shiping, Jin, Tengchuan, Nicoll, Roger A., Shi, Yun Stone, Sheng, Nengyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242971/
https://www.ncbi.nlm.nih.gov/pubmed/30451858
http://dx.doi.org/10.1038/s41467-018-07403-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242971/
https://www.ncbi.nlm.nih.gov/pubmed/30451858
http://dx.doi.org/10.1038/s41467-018-07403-7

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