Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

Flow of cerebrospinal fluid (CSF) through perivascular spaces (PVSs) in the brain is important for clearance of metabolic waste. Arterial pulsations are thought to drive flow, but this has never been quantitatively shown. We used particle tracking to quantify CSF flow velocities in PVSs of live mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Mestre, Humberto, Tithof, Jeffrey, Du, Ting, Song, Wei, Peng, Weiguo, Sweeney, Amanda M., Olveda, Genaro, Thomas, John H., Nedergaard, Maiken, Kelley, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242982/
https://www.ncbi.nlm.nih.gov/pubmed/30451853
http://dx.doi.org/10.1038/s41467-018-07318-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242982/
https://www.ncbi.nlm.nih.gov/pubmed/30451853
http://dx.doi.org/10.1038/s41467-018-07318-3

Ejemplares similares