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Enhanced inter-compartmental Ca(2+) flux modulates mitochondrial metabolism and apoptotic threshold during aging
BACKGROUND: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxygen species (ROS) and executors of programmed cell d...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243020/ https://www.ncbi.nlm.nih.gov/pubmed/30458321 http://dx.doi.org/10.1016/j.redox.2018.11.003 |