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Enhanced inter-compartmental Ca(2+) flux modulates mitochondrial metabolism and apoptotic threshold during aging

BACKGROUND: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxygen species (ROS) and executors of programmed cell d...

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Detalles Bibliográficos
Autores principales: Madreiter-Sokolowski, Corina T., Waldeck-Weiermair, Markus, Bourguignon, Marie-Pierre, Villeneuve, Nicole, Gottschalk, Benjamin, Klec, Christiane, Stryeck, Sarah, Radulovic, Snjezana, Parichatikanond, Warisara, Frank, Saša, Madl, Tobias, Malli, Roland, Graier, Wolfgang F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243020/
https://www.ncbi.nlm.nih.gov/pubmed/30458321
http://dx.doi.org/10.1016/j.redox.2018.11.003