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A Role for MK2 in Enhancing Neutrophil-Derived ROS Production and Aggravating Liver Ischemia/Reperfusion Injury

Increased inflammatory responses and enhanced reactive oxygen species contribute to hepatic ischemia/reperfusion (I/R) injury, however the modulatory mechanisms haven't been completely unveiled. Here, we report that genetic deficiency of MAPK-activated protein kinase 2 (MK2) protected against h...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Wu, Qiong, Nie, Yunjuan, Cheng, Ni, Wang, Rui, Wang, Gang, Zhang, Dan, He, Huiqiong, Ye, Richard D., Qian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243022/
https://www.ncbi.nlm.nih.gov/pubmed/30483268
http://dx.doi.org/10.3389/fimmu.2018.02610