mGlu5 Receptor Blockade Within the Nucleus Accumbens Shell Reduces Behavioral Indices of Alcohol Withdrawal-Induced Anxiety in Mice

Withdrawal from binge-drinking increases negative affect, coinciding with increased expression of the metabotropic glutamate receptor 5 (mGlu5) within the shell of the nucleus accumbens (AcbSh). Supporting a causal-effect relationship, systemic treatment with the mGlu5 receptor antagonist MTEP [3-((...

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Detalles Bibliográficos
Autores principales: Lee, Kaziya M., Coelho, Michal A., Class, MacKayla A., Sern, Kimberly R., Bocz, Mark D., Szumlinski, Karen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243038/
https://www.ncbi.nlm.nih.gov/pubmed/30483137
http://dx.doi.org/10.3389/fphar.2018.01306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243038/
https://www.ncbi.nlm.nih.gov/pubmed/30483137
http://dx.doi.org/10.3389/fphar.2018.01306

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