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The Hypervariable Loops of Free TCRs Sample Multiple Distinct Metastable Conformations in Solution
CD4(+) and CD8(+) αβ T cell antigen recognition is determined by the interaction between the TCR Complementarity Determining Region (CDR) loops and the peptide-presenting MHC complex. These T cells are known for their ability to recognize multiple pMHC complexes, and for a necessary promiscuity that...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243104/ https://www.ncbi.nlm.nih.gov/pubmed/30483515 http://dx.doi.org/10.3389/fmolb.2018.00095 |