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Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice

We investigated the different patterns of neurodegeneration and glia activation in CA1 and CA3 hippocampal areas of TgCRND8 mice. The main feature of this transgenic model is the rapid development of the amyloid pathology, which starts already at 3 months of age. We performed immunohistochemical ana...

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Detalles Bibliográficos
Autores principales: Ugolini, Filippo, Lana, Daniele, Nardiello, Pamela, Nosi, Daniele, Pantano, Daniela, Casamenti, Fiorella, Giovannini, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243135/
https://www.ncbi.nlm.nih.gov/pubmed/30483118
http://dx.doi.org/10.3389/fnagi.2018.00372