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Cervical skin denervation associates with alpha‐synuclein aggregates in Parkinson disease

OBJECTIVE: Autonomic nervous system is involved at the onset of Parkinson disease (PD), and alpha‐synuclein (α‐Syn) and its phosphorylated form (p‐αSyn) have been detected in dermal autonomic nerve fibers of PD. We assessed disease specific conformation variant of α‐Syn immunoreactivity in cutaneous...

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Detalles Bibliográficos
Autores principales: Melli, Giorgia, Vacchi, Elena, Biemmi, Vanessa, Galati, Salvatore, Staedler, Claudio, Ambrosini, Roberto, Kaelin‐Lang, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243385/
https://www.ncbi.nlm.nih.gov/pubmed/30480033
http://dx.doi.org/10.1002/acn3.669