Methanomethylophilus alvus Mx1201 Provides Basis for Mutual Orthogonal Pyrrolysyl tRNA/Aminoacyl-tRNA Synthetase Pairs in Mammalian Cells

[Image: see text] Genetic code expansion via stop codon suppression is a powerful technique for engineering proteins in mammalian cells with site-specifically encoded noncanonical amino acids (ncAAs). Current methods rely on very few available tRNA/aminoacyl-tRNA synthetase pairs orthogonal in mamma...

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Detalles Bibliográficos
Autores principales: Meineke, Birthe, Heimgärtner, Johannes, Lafranchi, Lorenzo, Elsässer, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243396/
https://www.ncbi.nlm.nih.gov/pubmed/30260624
http://dx.doi.org/10.1021/acschembio.8b00571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243396/
https://www.ncbi.nlm.nih.gov/pubmed/30260624
http://dx.doi.org/10.1021/acschembio.8b00571

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