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Effect of VEGFR, PDGFR and PI3K/mTOR Targeting in Glioblastoma

Resistance to targeted therapy is a well known obstacle in cancer therapy. The cross-talk between several growth factor receptors generates redundancy in their intracellular pathways that usually mediates resistance to receptor targeted therapy. Simultaneous inactivation of two or more growth factor...

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Detalles Bibliográficos
Autores principales: PURCARU, S.O., TACHE, D.E., SERBAN, F., FOLCUTI, R.M., GEORGESCU, A.M., STOVICEK, P.O., DANCIULESCU, M.M., TATARANU, L.G., DRICU, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243508/
https://www.ncbi.nlm.nih.gov/pubmed/30538838
http://dx.doi.org/10.12865/CHSJ.41.04.06