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Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood–brain barrier transport

The blood–brain barrier (BBB) hampers the delivery of therapeutic proteins into the brain. BBB-shuttle peptides have been conjugated to therapeutic payloads to increase the permeability of these molecules. However, most BBB-shuttles have several limitations, such as a lack of resistance to proteases...

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Detalles Bibliográficos
Autores principales:	Díaz-Perlas, Cristina, Oller-Salvia, Benjamí, Sánchez-Navarro, Macarena, Teixidó, Meritxell, Giralt, Ernest
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243681/ https://www.ncbi.nlm.nih.gov/pubmed/30542590 http://dx.doi.org/10.1039/c8sc02415d

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