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Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway

BACKGROUND: The purpose of the study was to investigate the functional roles of phosphatase in regenerating liver-3 (PRL-3) in hepatocellular carcinoma (HCC), as well as the related molecular mechanisms. MATERIAL/METHODS: HCC tissues and adjacent normal tissues were collected from 124 HCC patients....

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Detalles Bibliográficos
Autores principales: Li, Bing-Hui, Wang, Yang, Wang, Chao-Yang, Zhao, Ming-Juan, Deng, Tong, Ren, Xue-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243833/
https://www.ncbi.nlm.nih.gov/pubmed/30418964
http://dx.doi.org/10.12659/MSM.913307