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Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation

Annexin A1 (ANXA1) is dysregulated in the various tumors. However, the role and mechanism of ANXA1 in the cancers are poorly understood. In this study, we first showed a clinically positive correlation between ANXA1 and autophagy-associated protein SQSTM1 expression in nasopharyngeal carcinoma (NPC)...

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Detalles Bibliográficos
Autores principales: Zhu, Jin-Feng, Huang, Wei, Yi, Hong-Mei, Xiao, Ta, Li, Jiao-Yang, Feng, Juan, Yi, Hong, Lu, Shan-Shan, Li, Xin-Hui, Lu, Rou-Huang, He, Qiu-Yan, Xiao, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244011/
https://www.ncbi.nlm.nih.gov/pubmed/30459351
http://dx.doi.org/10.1038/s41419-018-1204-7