Rationalising drug delivery using nanoparticles: a combined simulation and immunology study of GnRH adsorbed to silica nanoparticles

Silica nanoparticles (SiNPs) have been shown to have significant potential for drug delivery and as adjuvants for vaccines. We have simulated the adsorption of GnRH-I (gonadotrophin releasing hormone I) and a cysteine-tagged modification (cys-GnRH-I) to model silica surfaces, as well as its conjugat...

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Detalles Bibliográficos
Autores principales: Connell, David J., Gebril, Ayman, Khan, Mohammad A. H., Patwardhan, Siddharth V., Kubiak-Ossowska, Karina, Ferro, Valerie A., Mulheran, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244087/
https://www.ncbi.nlm.nih.gov/pubmed/30459397
http://dx.doi.org/10.1038/s41598-018-35143-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244087/
https://www.ncbi.nlm.nih.gov/pubmed/30459397
http://dx.doi.org/10.1038/s41598-018-35143-7

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