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Rationalising drug delivery using nanoparticles: a combined simulation and immunology study of GnRH adsorbed to silica nanoparticles
Silica nanoparticles (SiNPs) have been shown to have significant potential for drug delivery and as adjuvants for vaccines. We have simulated the adsorption of GnRH-I (gonadotrophin releasing hormone I) and a cysteine-tagged modification (cys-GnRH-I) to model silica surfaces, as well as its conjugat...
Autores principales: | Connell, David J., Gebril, Ayman, Khan, Mohammad A. H., Patwardhan, Siddharth V., Kubiak-Ossowska, Karina, Ferro, Valerie A., Mulheran, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244087/ https://www.ncbi.nlm.nih.gov/pubmed/30459397 http://dx.doi.org/10.1038/s41598-018-35143-7 |
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