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Apigenin suppresses the stem cell-like properties of triple-negative breast cancer cells by inhibiting YAP/TAZ activity

Triple-negative breast cancer (TNBC) remains a clinical challenge because of the absence of effective therapeutic targets. In TNBC, overexpression of YAP and TAZ correlates with bioactivities of cancer stem cells (CSCs), high histological grade, resistance to chemotherapy, and metastasis. Thus, YAP/...

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Detalles Bibliográficos
Autores principales: Li, Ying-Wei, Xu, Jian, Zhu, Guo-Yuan, Huang, Zhu-Juan, Lu, Yan, Li, Xian-Qian, Wang, Neng, Zhang, Feng-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244166/
https://www.ncbi.nlm.nih.gov/pubmed/30479839
http://dx.doi.org/10.1038/s41420-018-0124-8