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Apigenin suppresses the stem cell-like properties of triple-negative breast cancer cells by inhibiting YAP/TAZ activity
Triple-negative breast cancer (TNBC) remains a clinical challenge because of the absence of effective therapeutic targets. In TNBC, overexpression of YAP and TAZ correlates with bioactivities of cancer stem cells (CSCs), high histological grade, resistance to chemotherapy, and metastasis. Thus, YAP/...
Autores principales: | Li, Ying-Wei, Xu, Jian, Zhu, Guo-Yuan, Huang, Zhu-Juan, Lu, Yan, Li, Xian-Qian, Wang, Neng, Zhang, Feng-Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244166/ https://www.ncbi.nlm.nih.gov/pubmed/30479839 http://dx.doi.org/10.1038/s41420-018-0124-8 |
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