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USP15 inhibits multiple myeloma cell apoptosis through activating a feedback loop with the transcription factor NF-κBp65

USP15 has been shown to stabilize transcription factors, to be amplified in many cancers and to mediate cancer cell survival. However, the underlying mechanism by which USP15 regulates multiple myeloma (MM) cell proliferation and apoptosis has not been established. Here, our results showed that USP1...

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Detalles Bibliográficos
Autores principales: Zhou, Lili, Jiang, Hua, Du, Juan, Li, Lu, Li, Rong, Lu, Jing, Fu, Weijun, Hou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244212/
https://www.ncbi.nlm.nih.gov/pubmed/30459344
http://dx.doi.org/10.1038/s12276-018-0180-4