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Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD

Chronic obstructive pulmonary disease (COPD) comprises multiple phenotypes such as airflow obstruction, emphysema, and frequent episodes of acute worsening of respiratory symptoms, known as exacerbations. The goal of this pilot study was to test the usefulness of unbiased metabolomics and transcript...

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Detalles Bibliográficos
Autores principales: Cruickshank-Quinn, Charmion I., Jacobson, Sean, Hughes, Grant, Powell, Roger L., Petrache, Irina, Kechris, Katerina, Bowler, Russell, Reisdorph, Nichole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244246/
https://www.ncbi.nlm.nih.gov/pubmed/30459441
http://dx.doi.org/10.1038/s41598-018-35372-w