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Bimodal sensing of guidance cues in mechanically distinct microenvironments

Contact guidance due to extracellular matrix architecture is a key regulator of carcinoma invasion and metastasis, yet our understanding of how cells sense guidance cues is limited. Here, using a platform with variable stiffness that facilitates uniaxial or biaxial matrix cues, or competing E-cadher...

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Detalles Bibliográficos
Autores principales: Tabdanov, Erdem D., Puram, Vikram V., Win, Zaw, Alamgir, Ashab, Alford, Patrick W., Provenzano, Paolo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244288/
https://www.ncbi.nlm.nih.gov/pubmed/30459308
http://dx.doi.org/10.1038/s41467-018-07290-y