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Bimodal sensing of guidance cues in mechanically distinct microenvironments
Contact guidance due to extracellular matrix architecture is a key regulator of carcinoma invasion and metastasis, yet our understanding of how cells sense guidance cues is limited. Here, using a platform with variable stiffness that facilitates uniaxial or biaxial matrix cues, or competing E-cadher...
Autores principales: | Tabdanov, Erdem D., Puram, Vikram V., Win, Zaw, Alamgir, Ashab, Alford, Patrick W., Provenzano, Paolo P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244288/ https://www.ncbi.nlm.nih.gov/pubmed/30459308 http://dx.doi.org/10.1038/s41467-018-07290-y |
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